Ohio State vs Northwestern Prediction, Odds: 2022 Week 10 College Football Picks, Best Bets From Proven Model

The mighty Ohio Buckeyes will look to keep their momentum going Saturday when they take on the struggling Northwestern Wildcats in a Big Ten college football showdown. Kickoff is set for noon ET by Ryan Field. The Buckeyes (8-0, 5-0) just earned the No. 2 spot in the first edition of the College Football Playoff rankings for the 2022 season. They need to keep winning to maintain that ranking and keep up with the opposition and No. 5-ranked Michigan (8-0, 5-0) in the Big Ten East standings ahead of their anticipated clash three weeks from Saturday. The Wildcats (1-7, 1-4) have snapped a seven-game hitting streak since winning their season opener.

The Buckeyes are 38-point favorites and the over/under for total points scored is 55.5 in the latest Ohio State vs. Northwestern from Caesars Sportsbook. Before you lock in any Northwestern vs. Ohio State picks, you need to check out the college football predictions and betting tips from SportsLine’s advanced computer model.

The SportsLine projection model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a staggering profit of nearly $3,000 for $100 players on college football’s top picks against the spread. Anyone who has followed it has seen tremendous returns.

Now, the model has Ohio State vs. Northwestern in its sights and has locked in its picks and CFB predictions. You can head over to SportsLine now to check out the model options. Here are several college football odds and betting lines for Northwestern vs. Ohio State:

  • Ohio State vs. Northwestern point spread: Ohio State -38
  • Ohio State vs. Northwestern over/under Total Rating Points: 55.5
  • NU: The Wildcats have covered the spread in three of their last five conference games as a double-digit underdog.
  • OSU: The road team is 5-1 against the spread in the last six meetings in this rivalry.
  • Ohio vs. Northwestern picks: See the picks at SportsLine

Because Ohio State can cover

When the Buckeyes are on offense, it often seems like they can score almost at will, especially against smaller opponents. They’re averaging 49 points per game, which ranks No. 4 nationally and could easily be higher if not for the numerous second-half outbursts that have seen the reserves get significant playing time. Plus, two weeks ago they scored 54 on a stout Iowa defense that’s allowing just 15.6 points per game.

Heisman candidate CJ Stroud has picked apart opposing defensive units with incredible efficiency. The junior has completed 70.3% of his passes for 2,377 yards and 29 touchdowns against four interceptions. The Buckeyes should be motivated to stay sharp as they prepare for a late-season series that includes a visit to an explosive and upset Maryland team, followed by a matchup with Michigan that will likely be for a playoff spot conference title and could serve as the eliminator for a CFP bid.

Because Northwestern can cover

The Wildcats appeared resilient and poised, both key players under longtime coach Pat Fitzgerald, in their Week 1 win over Nebraska. They overcame an 11-point deficit for a 31-28 win, but that win was the highlight of the season so far.

The Wildcats were tied the following week and lost to Duke before suffering non-conference home losses to Southern Illinois and Miami-Ohio. They’ve been plagued by injuries, bad breaks and a limited offense that’s yielding just 17.9 points per game. Despite this, four of their losses were by single digits as they managed to stay competitive in most games. Four weeks ago, they lost 17-7 at Penn State as underdogs by nearly four touchdowns and kept it a one-score game most of the way.

Northwestern has maintained a respectable scoring defense (28.8 ppg) using a conservative defensive approach designed to prevent big plays and force opponents to slowly drive the length of the court. For example, both of Penn State’s touchdowns came in games that went seven plays, and the Wildcats forced the Nittany Lions to punt five times.

How to make Northwestern vs. Ohio State picks

SportsLine’s model leans toward the total, projecting a total of 58 points. The model also says that one side of the spread occurs in well over 60% of the simulations. You can see the model’s CFB options only at SportsLine.

So who wins Ohio State vs. Northwestern? And which side of the spread hits over 60% of the simulations? Visit SportsLine now to see which side of the spread to jump on, all from the model who crushed his college football picks and find out.

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