‘Magic mushroom’ treatment for depression inches closer to approval

Psilocybinhallucinogen in “magic mushrooms,” may help treat severe depression, according to results of the largest trial of the treatment ever.

Early data from the trial were released in November 2021, but these results were not peer-reviewed at that time. The new peer-reviewed report, published Wednesday (November 2) in the New England Journal of Medicine (opens in new tab)It comes as trial organizers prepare to begin an even larger trial, called a Phase 3 trial, which will provide the data needed for Food and Drug Administration (FDA) approval.

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