College football odds, picks, predictions, best bets for Week 12: PC likes Cincinnati, Oklahoma State

The Week 12 college football schedule has just two matchups between top-25 teams, and both of those games will come in the West in the Pac-12. No. 7 USC will face No. 16 UCLA in an 8 p.m. ET and No. 10 Utah will visit No. 12 Oregon at 10:30 p.m. ET. The Trojans are 2.5-point favorites according to the latest Week 12 college football odds from Caesars Sportsbook, while the Utes are 2-point favorites on the road.

Meanwhile, the No. 4 TCU will face Baylor in a crucial Big 12 road game. The Horned Frogs are 2-point favorites on the road according to the Week 12 college football lines as they try to extend a 10-game winning streak to keep their College Football Playoff hopes alive. Before making any Week 12 college football picks in these matchups or others, be sure to check out the latest college football predictions from SportsLine’s advanced computer model.

The SportsLine projection model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a staggering profit of nearly $3,000 for $100 players on college football’s top picks against the spread. Anyone who has followed it has seen tremendous returns.

Now, she’s turned her attention to the latest Week 12 college football odds from Caesars and locked down picks for every FBS game. Head here to see each option.

Top college football predictions for Week 12

One of the college picks the model is high on in Week 12: No. 25 Cincinnati (-17) covers at Temple at 4 p.m. ET on Saturday. The Bearcats have two losses by a combined 11 points entering Saturday, and Luke Fickell’s team will need to keep the pedal to the metal while locked in a tight AAC matchup with UCF and Tulane. All three teams are 5-1 and with UCF holding the tiebreaker both teams and the top two teams advance to the AAC Championship.

Cincinnati narrowly escaped with a 27-25 win over East Carolina last week to move to 8-2 on the season, but now the Bearcats have a much easier matchup against the Owls in Stan Drayton’s first season as coach. Temple has lost five of six and allowed at least 450 yards of total offense in four of its last five games. The model projects that the bland defensive unit is just what the Cincinnati offense needs to get back on track, projecting the Bearcats to score 40 and cover nearly 70 percent of the time.

Another of the model’s Week 12 college football picks: No. 22 Oklahoma State (+7.5) easily covers its game against Oklahoma on Saturday night at 7:30 p.m. ET. The Bedlam streak dates back to 1904 and the Sooners hold a prohibitive 90-19-7 advantage, but Oklahoma State will be riding high from a 37-33 win over Oklahoma last season. Now the Cowboys enter Saturday’s matchup after a tough 20-14 victory over Iowa State last week to end a two-game sweep.

The defense forced five turnovers in that game and limited Iowa State to 333 yards of total offense and just 59 yards on the ground. With Oklahoma running the ball nearly 60% of the time this season, the Sooners could have some trouble with Mike Gundy’s defense. The model also projects nearly 300 yards of total offense for Spencer Sanders, who is expected to deal with a shoulder injury, with Oklahoma State covering nearly 70% of the simulations and even winning outright more than 50% of the time . See what other groups the model likes here.

How to make Week 12 college football picks

The model also has a call for who wins and who covers in every other FBS matchup in Week 12, and says several top-20 teams will fall hard. You can only get every pick for every game on SportsLine.

So, what college football picks can you make with confidence? And which top-20 teams are falling hard? Check out the latest college football odds below, then visit SportsLine to see which teams are winning and covering the spread, all from a proven computer model that has returned nearly $3,000 in winnings over the past six-plus seasons and find out.

College Football Odds for Week 12 (via Caesars)

Check out our full Week 12 football picks, odds and predictions here

Saturday, November 19

Illinois at Michigan (-17.5, 43)

Selected game | Michigan Wolverines vs. Illinois Fighting Illini

TCU at Baylor (+2, 56.5)

Selected game | Baylor Bears vs. TCU Horned Frogs

Kansas State at West Virginia (+7.5, 55)

Selected game | West Virginia Mountaineers vs. Kansas State Wildcats

Georgia Tech at North Carolina (-21, 63)

Selected game | North Carolina Tar Heels vs. Georgia Tech Yellow Jackets

Miami (FL) at Clemson (-19, 46.5)

Selected game | Clemson Tigers vs. Miami (FL) Hurricanes

Georgia at Kentucky (+22.5, 49)

Selected game | Kentucky Wildcats vs. Georgia Bulldogs

NC State at Louisville (-5, 47.5)

Selected game | Louisville Cardinals vs. NC State Wolfpack

Ole Miss at Arkansas (+3, 58.5)

Selected game | Arkansas Razorbacks vs. Ole Miss Rebels

Tennessee at South Carolina (+22, 66)

Selected game | South Carolina Gamecocks vs. Tennessee Volunteers

Oklahoma State at Oklahoma (-7.5, 65)

Selected game | Oklahoma Sooners vs. Oklahoma State Cowboys

USC at UCLA (+2.5, 74.5)

Selected game | UCLA Bruins vs. USC Trojans

Utah at Oregon (-3, 62.5)

Selected game | Oregon Ducks vs. Utah Utes

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